Evidently eight fatal cases of Clostridium sordellii contamination in ladies who had just given birth have also been reported in medical literature and the CDC says last month it provides discovered reports of two fatal situations of the same an infection in women who had miscarriages in their second trimester. Some experts wonder if RU-486 might suppress the disease fighting capability, which would increase susceptibility to bacteria currently present in the vaginal canal. They say pregnancy suppresses the immune system, and the dilation of the cervix, whether due to abortion, childbirth or miscarriage, which may let bacteria penetrate deeper in to the body also.The T12PR12 group was smaller compared to the other three organizations intentionally, for an exploratory evaluation of a very brief duration of therapy; the study-analysis plan didn’t include a comparison of this group with the PR48 group. Four planned interim analyses of security and efficacy were conducted through the scholarly study at prespecified milestones, as was one analysis of safety only, when 80 individuals had completed 12 weeks of treatment. Data administration and interim analyses had been performed by the Duke Clinical Research Institute; after the scholarly research was unblinded, data analyses were performed by Vertex Pharmaceuticals, the sponsor. An independent data monitoring committee reviewed the total results of all interim analyses.