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The principal efficacy endpoint.

Chey, MD, Professor of Internal Medicine, University of Michigan, Ann Arbor. More than 30 million people suffer from CIC and IBS-C and the outcomes of this Phase IIb trial additional support the potential of A3309 to end up being a significant treatment for these sufferers. The info in the trial offered today give a solid bottom for moving forward into Phase III in 2011 stated Hans Graffner, Chief Medical Officer of Albireo. Albireo expects to present detailed results of the trial A3309-002 at upcoming scientific conferences.. Albireo reports positive results from A3309 Stage IIb study in chronic idiopathic constipation Albireo today announced positive top-line results from a Stage IIb study in chronic idiopathic constipation assessing efficacy and basic safety of three different dose amounts of the investigational drug A3309 during an eight week trial. Continue reading

John Eikelboom Read more about this drug.

Stuart J. Connolly, M Read more about this drug .D., Michael D. Ezekowitz, M.B., Ch.B., D.Phil., Salim Yusuf, F.R.C.P.C., D.Phil., John Eikelboom, M.D., Jonas Oldgren, M.D., Ph.D., Amit Parekh, M.D., Janice Pogue, M.Sc., Paul A. Reilly, Ph.D., Ellison Themeles, B.A., Jeanne Varrone, M.D., Susan Wang, Ph.D., Marco Alings, M.D., Ph.D., Denis Xavier, M.D., Jun Zhu, M.D., Rafael Diaz, M.D., Basil S. Lewis, M.D., Harald Darius, M.D., Hans-Christoph Diener, M.D., Ph.D., Campbell D. Joyner, M.D., Lars Wallentin, M.D., Ph.D., and the RE-LY Steering Committee and Investigators: Dabigatran versus Warfarin in Individuals with Atrial Fibrillation Atrial fibrillation escalates the risks of stroke and death. Continue reading

35-year megadrought to strike the American southwest In the summertime of 2014.

35-year ‘megadrought’ to strike the American southwest In the summertime of 2014, social media sites were awash with movies of people taking the ‘ALS ice bucket challenge.’ The ALS marketing stunt captured on like wildfire, prompting thousands of social press users to pour buckets of ice water over their heads. As the organization gained attention, $12.5 million in donations over the course of a year were funneled to a staff of eleven executives sitting near the top of the ALS pyramid. As the group of executives raked in an incredible number of wasted donation dollars, an incredible number of gallons of drinking water were wasted through the entire U also.S. Continue reading

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