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To get the latest urology news releases from UroToday access,further. And Axon Bridging After InjuryLaura Taylor, Leonard Jones, Tuszynski and Armin Blesch neurotrophic factors can promote axon growth after spinal cord injury. If, for example genetically engineered cells grafted the neurotrophin NT-3 in the site of injury, to grow into the lesion axons. However, these axons are rarely leaving the graft to the adjacent spinal cord innervate. This week, Taylor et al. Tries, this stumbling block to overcome the regeneration. They transplanted grafts of syngeneic marrow stromal cells overexpressing NT-3 in the dorsal column lesions in the adult rat spinal cord, the fiber tract leads ascending sensory axons. The authors then lentiviral vectors injected NT-3 expression at sites rostral to the graft, creating an enhanced gradient of neurotrophic factor axons lead growth. Injected into animals, axons in fact the gap and extends beyond the graft but limit not go further than 500? although NT-3 gradients expanded further. The growth pattern was not strictly chemo tropic ‘.
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