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The study used a computer simulation model, the hypothetical patient with the FOLFIRI chemotherapy in metastatic colorectal cancer treated follows. The model assumed that under usual care, patients received a full dose of irinotecan. An important example of testing irinotecan dose was 25 % among persons who reduced on the basis of genetic tests than with the UGT1A1* 28 variant allele. The dose reduction in the Food and Drug Administration approved drug label given to minimize cases of neutropenia. Schackman Schackman, senior author of the study, says, cost-benefit evaluation of pharmacogenetic tests important findings both create in the clinical and economic value of these new treatment paradigms, but few of these types of studies have been done is important is that. These studies also allow us to define in economic terms the value of additional comparative effectiveness research. In this case, we have determined that further research should be carried out up to $ 22,000 to the risks and benefits of dose reduction study based on the results test test. Dr. Schackman is associate professor of public health and director of the Department of Health Policy in the Department of Public Health at Weill Cornell Medical College.
Researchers asked whether zinc could be help avoid otitis media. The reviewers found 12 related studies of healthy children aged between five years ago or younger who increased the 10 low – and middle-income countries.
Are frequent supplements avoid middle ear infections: Evidence Is Weak – not will find a new Cochrane Review clear evidence that the ingestion zinc supplementation to reduce the incidence of middle ear infections or otitis media to healthy children .