Furthermore, the FDA extended the approval of Benicar in 2010 2010 to take care of the around 3.6 million hypertensive kids in the United States, which could have increased the real number of prescriptions written. READ ON >> 5. HIV Three different HIV treatments appeared on the 50 best-selling brand-name medicines list: efavirenz/emtricitabine/tenofovir disoproxil fumarate , emtricitabine/tenofovir disoproxil fumarate , and elvitegravir/cobicistat/ emtricitabine/tenofovir . Together, these medicines generated a lot more than $5.5 billion in sales between April 2014 and March 2015. However, none of these treatments appear on the 50 most-recommended list, suggesting low patient access.All other hypothesis testing was two-sided with a significance level of 0.05, with Hochberg adjustment used to control for multiple testing. All P values have been adjusted for multiple tests unless specified otherwise. Key safety end factors included adverse events occurring during treatment, laboratory values, and the presence of anti-evolocumab antibodies. Protection analyses were conducted by using descriptive statistics that were predicated on observed data without imputation. Adverse events were coded with the use of the Medical Dictionary for Regulatory Actions, version 16.1. Results Sufferers From January 2012 through November 2013 The analysis was conducted. Of the 2120 sufferers who were screened, 905 underwent randomization, 901 received at least one dosage of a report drug, and 800 completed 52 weeks of treatment .