This first completed Phase III research, entitled ODYSSEY MONO, examined the new lower 75-mg dose of alirocumab subcutaneously every 14 days as a monotherapy versus ezetimibe 10 mg per os each day as a control. Inclusion requirements included individuals with an LDL-C between 100 mg/dl and 190 mg/dl (.. Alirocumab shows promise as treatment to reduce LDL-cholesterol in Phase III study A recently published clinical trial record reviewing the first completed Stage III research in the ODYSSEY advancement program shows that alirocumab showed significantly better LDL-C lowering than ezetimibe, with a comparable safety profile to ezetimibe.They discovered just 11 % of these protection checks involved booster seats for kids between your ages of 4 and 7, while about 50 percent of these inspections had been for rear-facing infant car seats. Meanwhile, about one-third of the booster chairs examined required an adjustment that made them safer. The findings were published in the Journal of Trauma recently. Oftentimes, children aged 4 and older in these inspections were there because of a car seat look for a younger sibling – – not to have their own seat checked. The researchers described many safety initiatives focus on car seat inspections for toddlers and infants, while few address safety issues connected with older kids’ booster seats. Lead author Amber Kroeker, who conducted the scholarly study even though a researcher at the University of Michigan, said, Study after research shows that caregivers often want support and direction when choosing and installing child restraints and that they are often with them incorrectly, which puts child passengers at unnecessary risk of harm.